Sodium-extruding and calcium-extruding sodium/calcium exchangers display similar calcium affinities

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Sodium-extruding and calcium-extruding sodium/calcium exchangers display similar calcium affinities.

Na+/Ca2+ exchange activities in purely inside-out and mixed inside-out and right-side-out fish enterocyte basolateral plasma membrane vesicle preparations display equal affinities for Ca2+, showing that only the intracellular Ca2+ transport site of the Na+/Ca2+ exchanger is detected in experiments on vesicle preparations with mixed orientation. Therefore, Ca2+ pump and Na+/Ca2+ exchange activit...

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Calcium ions play a critical role in neurotransmitter release. The cytosolic Ca2+ concentration ([Ca2+]cyt) at nerve terminals must therefore be carefully controlled. Several different mechanisms, including a plasmalemmal Na/Ca exchanger, are involved in regulating [Ca2+]cyt. We employed immunofluorescence microscopy with polyclonal antiserum raised against dog cardiac sarcolemmal Na/Ca exchang...

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ژورنال

عنوان ژورنال: Journal of Experimental Biology

سال: 1992

ISSN: 1477-9145,0022-0949

DOI: 10.1242/jeb.168.1.151